Cyclohexyl isothiocyanate → 3-Cyclohexyl-1-[4-(2-formylhydrazino)-3-methoxyphenyl]thiourea

HRID 437518Notes

Reaction equation

HRID 437518 reaction equation
[CH:1]([NH:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][C:6]=1[O:12][CH3:13])=[O:2].[CH:14]1([N:20]=[C:21]=[S:22])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([NH:20][C:21](=[S:22])[NH:11][C:8]2[CH:9]=[CH:10][C:5]([NH:4][NH:3][CH:1]=[O:2])=[C:6]([O:12][CH3:13])[CH:7]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 14289Cyclohexyl isothiocyanateHCID 214278421-Formyl-2-(4-amino-2-methoxyphenyl)hydrazine

Product 1

HCID 214278253-Cyclohexyl-1-[4-(2-formylhydrazino)-3-methoxyphenyl]thiourea

Procedure

Procedure (11.) was employed with 1-formyl-2-(4-amino-2-methoxyphenyl)hydrazine (1.2 g, 0.0066 mole) and cyclohexyl isothiocyanate (0.93 g, 0.0066 mole). Yield 0.50 g (24%), m.p. 131°-133° C.

Sources & evidence

ORD record
ord-eda235568a5a431ba0b851a140d89fbd
Source dataset
uspto-grants-1977_06
Patent number
US04031127

Reaction notes

Loading…