Aluminium lithium hydride → HCID 21428712, compound

HRID 437567Notes

Reaction equation

HRID 437567 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([C:10](=O)[C:11]([N:13]2[CH2:18][CH2:17][CH:16]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:15][CH2:14]2)=O)=[CH:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[O:19]([CH:16]1[CH2:15][CH2:14][N:13]([CH2:11][CH2:10][C:3]2[C:4]3[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=3)[NH:1][CH:2]=2)[CH2:18][CH2:17]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 214286921-(1H-Indol-3-yl)-2-(4-phenoxy-1-piperidinyl)-1,2-ethanedione

Product 1

HCID 21428712HCID 21428712, compound

Procedure

By following the manipulative procedure described in Example 4(c), 5.0 g of 1-(indol-3-ylglyoxyloyl)-4-phenoxypiperidine are reacted with 2.8 g of lithium aluminum hydride to give white flakes of 3-[2-(4-phenoxypiperidyl)ethyl]indole, m.p. 123°-125° C.

Sources & evidence

ORD record
ord-ee90d9a277af4b288f3daebdb1836dd5
Source dataset
uspto-grants-1977_06
Patent number
US04031221

Reaction notes

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