Aluminium lithium hydride → HCID 21428707, compound

Participants

Reaction Steps

By following the manipulative procedure described in Example 2(d), 5.5 g of lithium aluminum hydride in 160 ml. of tetrahydrofuran and 12.0 g of 1-(2-methylindol-3-ylglyoxyloyl)-4-(p-fluorophenoxy)piperidine in 120 ml. of tetrahydrofuran are reacted to produce a white solid. The solid is recrystallized from an ethanol and water mixture (charcoal treatment) to give a white powder of 3-{2-[4-(p-fluorophenoxy)piperidyl]ethyl}-2-methylindole, m.p. 97°-99° C.

Provenance & Evidence