Aluminium lithium hydride → HCID 21428701, compound

Participants

Reaction Steps

By following the manipulative procedure described in Example 2(d), 8.0 g of lithium aluminum hydride in 235 ml. of tetrahydrofuran and 18.0 g of 4-(p-fluorophenoxy)-1-(5-methoxyindol-3-ylglyoxyloyl)piperidine in 190 ml. of tetrahydrofuran are reacted to produce a white solid. The solid is recrystallized twice from 95% ethanol (charcoal treatment) to give white crystals of 3-{2-[4-(p-fluorophenoxy)piperidyl]ethyl}5-methoxyindole, m.p. 132°-134° C.

Provenance & Evidence