HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → HCID 21428720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 1-[3-(4-Fluorophenoxy)-1-azetidinyl]-2-(1H-indol-3-yl)-1,2-ethanedione | HCID 21428713 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21428720 | HCID 21428720 | — |
Reaction Steps
By following the manipulative procedure described in Example 2(d), 0.7 g of lithium aluminum hydride in 30 ml. of tetrahydrofuran and 1.5 g of 1-(indol-3-ylglyoxyloyl)-3-(p-fluorophenoxy)azetidine in 30 ml. of tetrahydrofuran are reacted to produce a white solid. The solid is recrystallized twice from an ethanol and water mixture to give colorless needles of 3-{2-[3-(p-fluorophenoxy)azetidinyl]ethyl}indole, m.p. 111°-113°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04031221 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-37a4ef8798cc40d3bea58bc272f6ee54 |
| Source note | uspto-grants-1977_06 |