HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 21428717, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 4-Phenyl-1-(phenylmethyl)-4-[4-(trifluoromethyl)phenoxy]piperidine | HCID 21428703 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 21428717 | HCID 21428717 | — |
Reaction Steps
A solution of 10.0 g of 1-benzyl-4-phenyl-4-(p-trifluoromethylphenoxy)piperidine and 4.1 g of phenylchloroformate in 100 ml. of toluene was refluxed for 17 hours. The toluene was removed under reduced pressure to give a colorless oil which when rubbed with a glass rod in the presence of hexane gave a white solid of 1-phenoxycarbonyl-4-phenyl-4-(p-trifluoromethylphenoxy)piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04031221 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-bdcd67b513d74288afbc06b08fb64a16 |
| Source note | uspto-grants-1977_06 |