Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

N,N-Bis-[3-(3,4-dihydro-4,4-dimethyl-7-amino-1,3-dioxo-2(1H)-isoquinolyl)-propyl]-amine and its monohydrochloride was prepared analogous to Example 52 from N,N-bis-[3-(3,4-dihydro-4,4-dimethyl-7-nitro-1,3-dioxo-2(1H)-isoquinolyl)-propyl]-ammonium nitrate. M.p. of the monohydrochloride: above 300° C (sintering from 285° C); yield: 1 gm (41% of theory) (monohydrochloride).

Provenance & Evidence