Hydrochloric Acid → Hydrochloric Acid

HRID 437591Notes

Reaction equation

HRID 437591 reaction equation
[N+]([O-])([O-])=O.[CH3:5][C:6]1([CH3:45])[C:15]2[C:10](=[CH:11][C:12]([N+:16]([O-])=O)=[CH:13][CH:14]=2)[C:9](=[O:19])[N:8]([CH2:20][CH2:21][CH2:22][NH2+:23][CH2:24][CH2:25][CH2:26][N:27]2[C:36](=[O:37])[C:35]([CH3:39])([CH3:38])[C:34]3[C:29](=[CH:30][C:31]([N+:40]([O-])=O)=[CH:32][CH:33]=3)[C:28]2=[O:43])[C:7]1=[O:44].[ClH:46]>>[CH3:5][C:6]1([CH3:45])[C:15]2[C:10](=[CH:11][C:12]([NH2:16])=[CH:13][CH:14]=2)[C:9](=[O:19])[N:8]([CH2:20][CH2:21][CH2:22][NH:23][CH2:24][CH2:25][CH2:26][N:27]2[C:36](=[O:37])[C:35]([CH3:38])([CH3:39])[C:34]3[C:29](=[CH:30][C:31]([NH2:40])=[CH:32][CH:33]=3)[C:28]2=[O:43])[C:7]1=[O:44].[ClH:46]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21428673HCID 21428673, compound

Product 2

HCID 313Hydrochloric AcidHCID 21428618HCID 21428618, compound

Procedure

N,N-Bis-[3-(3,4-dihydro-4,4-dimethyl-7-amino-1,3-dioxo-2(1H)-isoquinolyl)-propyl]-amine and its monohydrochloride was prepared analogous to Example 52 from N,N-bis-[3-(3,4-dihydro-4,4-dimethyl-7-nitro-1,3-dioxo-2(1H)-isoquinolyl)-propyl]-ammonium nitrate. M.p. of the monohydrochloride: above 300° C (sintering from 285° C); yield: 1 gm (41% of theory) (monohydrochloride).

Workup

  1. customabove 300° C (sintering from 285° C)

Sources & evidence

ORD record
ord-ede5fbbc863a4af0bd47744c95dd19c4
Source dataset
uspto-grants-1977_06
Patent number
US04031219

Reaction notes

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