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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 437769Generated: October 30, 2026

Methyl iodide → 1-Ethyl-2-phenyl-4-(trifluoromethyl)-1H-imidazole

https://huagongshe.com/reaction/437769

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantIodoethaneHCID 6340—
Reactant1-Methyl-2-phenyl-4-(trifluoromethyl)-1H-imidazoleHCID 15882114—
ReactantHCID 178506248HCID 178506248—
Product1-Ethyl-2-phenyl-4-(trifluoromethyl)-1H-imidazoleHCID 22759807—

Reaction Steps

By substituting equivalent amounts of ethyl iodide and 2-phenyl-4-trifluoromethylimidazole for the methyl iodide and 2-(2-pyridyl)-4(5)-trifluoromethylimidazole of Example 57 and following substantially the procedure described therein there is obtained 1-ethyl-2-phenyl-4-trifluoromethylimidazole, b.p., 160°-165° C. at 0.5 mm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04032522
Source datasetuspto-grants-1977_06
ORD IDord-b054b1e9d44d4f3690f5c50933d6deae
Source noteuspto-grants-1977_06