HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl cis(+/-)-6-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyrimidine-4-carboxylate → HCID 86648728, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl cis(+/-)-6-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyrimidine-4-carboxylate | HCID 86648725 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | HCID 86648728 | HCID 86648728 | 71.8% |
Reaction Steps
The same operation as in Example (160c) was performed using methyl cis(±)-6-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyrimidine-4-carboxylate obtained in Example (174c) (111 mg, 0.28 mmol) and a 10% palladium-carbon catalyst (130 mg), to obtain 53.5 mg of the title compound as a pale yellow oily substance. The resulting compound was used for the next reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-99ac05a6dfdd40429d7260c01fa1408e |
| Source note | uspto-grants-2013_09 |