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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43778Generated: October 29, 2026

Methyl cis(+/-)-6-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyrimidine-4-carboxylate → HCID 86648728, compound

https://huagongshe.com/reaction/43778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl cis(+/-)-6-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyrimidine-4-carboxylateHCID 86648725—
CatalystHCID 178418390HCID 178418390—
ProductHCID 86648728HCID 8664872871.8%

Reaction Steps

The same operation as in Example (160c) was performed using methyl cis(±)-6-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyrimidine-4-carboxylate obtained in Example (174c) (111 mg, 0.28 mmol) and a 10% palladium-carbon catalyst (130 mg), to obtain 53.5 mg of the title compound as a pale yellow oily substance. The resulting compound was used for the next reaction without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536197B2
Source datasetuspto-grants-2013_09
ORD IDord-99ac05a6dfdd40429d7260c01fa1408e
Source noteuspto-grants-2013_09