HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131730870, compound → Methyl cis(+/-)-3-(4-amino-3-ethoxypiperidin-1-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131730870 | HCID 131730870 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | Methyl cis(+/-)-3-(4-amino-3-ethoxypiperidin-1-yl)benzoate | HCID 86648736 | 22.7% |
Reaction Steps
The same operation as in Example (160c) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-ethoxypiperidin-1-yl)benzoate obtained in Example (48c) (155 mg, 0.38 mmol) and a 10% palladium-carbon catalyst (200 mg), to obtain 24 mg of the title compound as a pale yellow oily substance. The resulting compound was used for the next reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-3eb637e1c12740ca9820a5cdbc8d2cd8 |
| Source note | uspto-grants-2013_09 |