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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43786Generated: October 29, 2026

HCID 131730870, compound → Methyl cis(+/-)-3-(4-amino-3-ethoxypiperidin-1-yl)benzoate

https://huagongshe.com/reaction/43786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 131730870HCID 131730870—
CatalystHCID 178418390HCID 178418390—
ProductMethyl cis(+/-)-3-(4-amino-3-ethoxypiperidin-1-yl)benzoateHCID 8664873622.7%

Reaction Steps

The same operation as in Example (160c) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-ethoxypiperidin-1-yl)benzoate obtained in Example (48c) (155 mg, 0.38 mmol) and a 10% palladium-carbon catalyst (200 mg), to obtain 24 mg of the title compound as a pale yellow oily substance. The resulting compound was used for the next reaction without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536197B2
Source datasetuspto-grants-2013_09
ORD IDord-3eb637e1c12740ca9820a5cdbc8d2cd8
Source noteuspto-grants-2013_09