HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 437884Generated: October 25, 2026
Acetic Anhydride → 3-(2,4-Bis(dimethylamino)phenyl)-3-(4-(diethylamino)phenyl)-4,5,6,7-tetrachlorophthalide
https://huagongshe.com/reaction/437884
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1,3-Benzenediamine, N1,N1,N3,N3-tetramethyl- | HCID 89715 | — |
| Reactant | 3,4,5,6-Tetrachloro-2-carboxy-4'-diethylaminobenzophenone | HCID 19956611 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(2,4-Bis(dimethylamino)phenyl)-3-(4-(diethylamino)phenyl)-4,5,6,7-tetrachlorophthalide | HCID 53676727 | 48.2% |
Reaction Steps
A mixture of 2-(4-(diethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid (8.70 g.), N,N,N',N'-tetramethyl-m-phenylenediamine (3.61 g.) and acetic anhydride (5 ml.) was heated (to 90° C.). Addition of methanol (10 ml.) and slurrying the resulting product with methanol afforded 3-(2,4-bis(dimethylamino)phenyl)-3-(4-(diethylamino)phenyl)-4,5,6,7-tetrachlorophthalide (I: X= (CH3)2N, Y2 = H, Y4 = (CH3CH2)2N, Z4 = Z5 = Z6 = Z7 = Cl) (5.60 g., m.p. 206°-207.5° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04032527 |
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| Source dataset | uspto-grants-1977_06 |
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| ORD ID | ord-cba49c39658444328d68ab7295c09605 |
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| Source note | uspto-grants-1977_06 |
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