Bromoacetyl bromide → HCID 21427333, compound

HRID 437896Notes

Reaction equation

HRID 437896 reaction equation
BrCC(Br)=O.[CH3:6][C:7]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14](=[O:18])[CH2:15][CH2:16][CH3:17])[C:8]=1[NH2:9].[Br:19][CH2:20][CH2:21][C:22](Cl)=[O:23]>>[Br:19][CH2:20][CH2:21][C:22]([NH:9][C:8]1[C:10]([C:14](=[O:18])[CH2:15][CH2:16][CH3:17])=[CH:11][CH:12]=[CH:13][C:7]=1[CH3:6])=[O:23]

Participants

4

Reactant 3

HCID 61147Bromoacetyl bromideHCID 84944Propanoyl chloride, 3-bromo-HCID 15240473HCID 15240473, compound

Product 1

HCID 21427333HCID 21427333, compound

Procedure

In the same manner as in Example 1 but replacing 2-acetyl-6-methylaniline and bromoacetyl bromide by 2-methyl-6-n-butanoylaniline and 3-bromopropionyl chloride, there was obtained 3-bromo-2'-methyl-6'-n-butanoylpropionanilide. [B] Amination

Sources & evidence

ORD record
ord-b36d7d113d3849e0874401bdf4b7f64e
Source dataset
uspto-grants-1977_06
Patent number
US04032573

Reaction notes

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