HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131730871, compound → Ethyl cis(+/-)-2-(4-amino-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131730871 | HCID 131730871 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | Ethyl cis(+/-)-2-(4-amino-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate | HCID 86648743 | 18.5% |
Reaction Steps
The same operation as in Example (160c) was performed using ethyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate obtained in Example (180a) (207 mg, 0.48 mmol) and a 10% palladium-carbon catalyst (200 mg), to obtain 26.1 mg of the title compound as a yellow oily substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-9536d1429b49410b87d09dda64ceb9ae |
| Source note | uspto-grants-2013_09 |