Water → 2-Chlorobutyryl m-chlorobenzoyl peroxide

HRID 437931Notes

Reaction equation

HRID 437931 reaction equation
C(=O)([O-])[O-].[Na+].[Na+].O.[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([O:17][OH:18])=[O:16])[CH:10]=1.[Cl:19][CH:20]([CH2:24][CH3:25])[C:21](Cl)=[O:22]>C(Cl)(Cl)Cl>[Cl:8][C:9]1[CH:10]=[C:11]([CH:12]=[CH:13][CH:14]=1)[C:15]([O:17][O:18][C:21](=[O:22])[CH:20]([Cl:19])[CH2:24][CH3:25])=[O:16]

Participants

6

Reactant 4

HCID 962WaterHCID 10340Sodium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 1390532-Chlorobutanoyl chloride

Product 1

HCID 233454892-Chlorobutyryl m-chlorobenzoyl peroxideYield 97.7%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
-2 °C

Procedure

To 6.4 g. (0.06 moles) anhydrous sodium carbonate in 60 cc. H2O was added 10.2 g. (0.05 moles) of m-chloroperbenzoic acid of 84.35% purity. The stirred mixture was chilled to -2° C. and 8.5 g. (0.06 moles) 2-chlorobutyryl chloride in 30 cc. chloroform was added over 17 minutes. After a total reaction time of 60 minutes, the reaction was worked up as in Example I and gave 15.2 g. product. Product A.O. analysis: theory, 5.77; found, 5.15; 89.30% pure; 97.7% yield.

Workup

  1. customAfter a total reaction time of 60 minutes
  2. customgave 15.2 g

Sources & evidence

ORD record
ord-d8ede27eb410435b88bb259143489840
Source dataset
uspto-grants-1977_06
Patent number
US04032605

Reaction notes

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