HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178477851, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2H-Azepine, 3,4,5,6-tetrahydro-7-methoxy- | HCID 75657 | — |
| Reactant | 4-amino-6-chloro-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene hydrochloride | HCID 21427417 | — |
| Catalyst | Diethyl Ether | HCID 3283 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178477851 | HCID 178477851 | — |
Reaction Steps
5 ml of 98% ethanol and 10.0 g of caprolactim 0-methyl ether are added to 8.0 g of 4-amino-6-chloro-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene hydrochloride and are allowed to stand at room temperature while shaking occasionally. A few drops of ether are added to the resulting clear solution after 12 hours, whereupon the hydrochloride of the title compound crystallizes. M.Pt. decomp. from 185°, (recrystallized once from ethanol/ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04032640 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-c3df77681588463f9f6e45377778a906 |
| Source note | uspto-grants-1977_06 |