(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → HCID 178525813, compound

HRID 438004Notes

Reaction equation

HRID 438004 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[NH2:13][C@H:14]([C:21]([OH:23])=[O:22])[CH2:15][C:16]1[N:20]=[CH:19][NH:18][CH:17]=1>[Pd]>[OH:4][CH:3]([CH:5]([OH:6])[CH:7]([OH:8])[CH:9]([OH:10])[CH2:11][OH:12])[CH2:2][NH:13][C@H:14]([C:21]([OH:23])=[O:22])[CH2:15][C:16]1[N:20]=[CH:19][NH:18][CH:17]=1

Participants

4

Reactant 2

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 178419078HCID 178419078, compound

Product 1

HCID 178525813HCID 178525813, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The manufacture took place from D-glucose and L-(-)-histidine using palladium/activated carbon (10%) as a catalyst and yielded a product having a melting point of 165° to 170° C. (decomposition).

Workup

  1. customyielded a product

Sources & evidence

ORD record
ord-7c70bed456fb4997b6fe1cf69e1dbad3
Source dataset
uspto-grants-1977_06
Patent number
US04032676

Reaction notes

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