DL-Serine → N-(1,3,4,5,6-pentahydroxy-2-hexyl)-DL-serine

HRID 438017Notes

Reaction equation

HRID 438017 reaction equation
[OH:1][CH2:2][C:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])O)[OH:8])[OH:6])=[O:4].[NH2:13][CH:14]([C:17]([OH:19])=[O:18])[CH2:15][OH:16]>[Ni]>[OH:12][CH2:11][CH:9]([NH:13][CH:14]([C:17]([OH:19])=[O:18])[CH2:15][OH:16])[CH:7]([OH:8])[CH:5]([OH:6])[CH:3]([OH:4])[CH2:2][OH:1]

Participants

4

Reactant 2

HCID 617DL-SerineHCID 5984D-(-)-Fructose

Product 1

HCID 21427701N-(1,3,4,5,6-pentahydroxy-2-hexyl)-DL-serine

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The product, obtained in the form of a resin, was made from D-fructose and DL-serine using Raney nickel as a catalyst and heating for 2 hours to 50° C. and for 3 hours to 70° C.

Workup

  1. customThe product, obtained in the form of a resin
  2. temperatureheating for 2 hours to 50° C. and for 3 hours to 70° C.

Sources & evidence

ORD record
ord-15da283cddef4aceb96de02a8a1a87d8
Source dataset
uspto-grants-1977_06
Patent number
US04032676

Reaction notes

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