Benzenesulfonyl chloride → HCID 22616257, compound

HRID 439362Notes

Reaction equation

HRID 439362 reaction equation
[NH2:1][C:2]1[O:6][N:5]=[C:4]([CH3:7])[C:3]=1[Cl:8].[C:9]1([S:15](Cl)(=[O:17])=[O:16])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[Cl:8][C:3]1[C:4]([CH3:7])=[N:5][O:6][C:2]=1[NH:1][S:15]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:17])=[O:16]

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 105828224-Chloro-3-methyl-1,2-oxazol-5-amine

Product 1

HCID 22616257HCID 22616257, compoundYield 84%

Procedure

N-(4-Chloro-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared according to the method in Example 1b from 5-amino-4-chloro-3-methylisoxazole and benzenesuIfonyl chloride in 84% yield. The crude product was purified by recrystallization using hexanes/ethyl acetate, m.p. 140°-143° C.

Workup

  1. customThe crude product was purified by recrystallization

Sources & evidence

ORD record
ord-73e8996cdf724483978362e736bf221b
Source dataset
uspto-grants-1996_05
Patent number
US05514691

Reaction notes

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