HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dithiolane → Diethylether ethylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dithiolane | HCID 20970 | — |
| Reactant | N-(3-Aminopropyl)morpholine | HCID 61055 | — |
| Reactant | Ph2CHCO-Leu-Phe-COOEt | HCID 131719396 | — |
| Product | Diethylether ethylacetate | HCID 21584169 | 20% |
Reaction Steps
This compound was synthesized from 1,3-dithiolane derivative of Ph2CHCO-Leu-Phe-COOEt and N-aminopropylmorpholine, and purified by column chromatography using AcOEt followed by crystallization from AcOEt/ether (20% yield). Yellow solid, single spot on TLC, Rf =0.45 (AcOET/CH3OH 9:1), mp 158°-160° C. 1H NMR (CDCl3) ok, MS (FAB) m/e=627 (M+1). Anal: calcd. for C37H46N4O5, 626; C, 70.90; H, 7.40; N, 8.94. Found, C, 70.05; H, 7.43; N, 8.68.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05514694 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-a0c4a16670544afa9b01d20d786d28fa |
| Source note | uspto-grants-1996_05 |