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HRID439398

反应详情

EQUATION

反应方程式

HRID 439398 的结构方程式

REACTANTS

反应物

3
结构：C1CSCS1
HCID20970

1,3-Dithiolane

C3H6S2

结构：NCCCN1CCOCC1
HCID61055

4-Morpholinepropanamine

C7H16N2O

结构：CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(c1ccccc1)c1ccccc1
HCID131719396

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(C)=O.CCOCC
HCID21584169

未命名化合物

收率 20%

PROCEDURE

实验过程

This compound was synthesized from 1,3-dithiolane derivative of Ph2CHCO-Leu-Phe-COOEt and N-aminopropylmorpholine, and purified by column chromatography using AcOEt followed by crystallization from AcOEt/ether (20% yield). Yellow solid, single spot on TLC, Rf =0.45 (AcOET/CH3OH 9:1), mp 158°-160° C. 1H NMR (CDCl3) ok, MS (FAB) m/e=627 (M+1). Anal: calcd. for C37H46N4O5, 626; C, 70.90; H, 7.40; N, 8.94. Found, C, 70.05; H, 7.43; N, 8.68.

WORKUP

后处理

  1. custompurified by column chromatography