Benzaldehyde → HCID 45050441, compound

HRID 439615Notes

Reaction equation

[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][O:10][C:11](=[O:18])[CH2:12][CH2:13][C:14]([O:16][CH3:17])=[O:15]>>[CH3:9][O:10][C:11](=[O:18])[CH2:12]/[C:13](/[C:14]([O:16][CH3:17])=[O:15])=[CH:1]/[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 7820Dimethyl Succinate

Product 1

HCID 45050441HCID 45050441, compoundYield 4.9%

Procedure

Benzaldehyde (21.2 g) and succinic acid dimethyl ester (40.9 g) are treated in the same manner as in Reference Example 1, and the resulting product is purified by silica gel column chromatography to give (Z)-3-methoxycarbonyl-4-phenyl-3-butenoic acid methyl ester (2.3 g) as colorless syrup.

Workup

customthe resulting product is purified by silica gel column chromatography

Sources & evidence

ORD record: ord-9918b81697b84509a5d8402994611619
Source dataset: uspto-grants-1996_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05514815

Reaction notes

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