HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3,4,4-Trifluoro-3-butenoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3,4,4-Trifluoro-3-butenoic acid | HCID 15239174 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 3,4,4-Trifluoro-3-butenoyl chloride | HCID 10920789 | 74% |
Reaction Steps
A mixture of 3,4,4-trifluoro-3-butenoic acid (IV) (19.28 g, 138 mmol), oxalyl chloride (21.8 g, 172 mmol; 15 mL) and two drops of DMF was stirred for 6 hours and distilled at atmospheric pressure under nitrogen. The fraction boiling at 90°-98° C. was collected to give 16.1 g (74%) of the desired product as a dear liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05514717 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-429c01439d0b4bfbb68a5df9253276e0 |
| Source note | uspto-grants-1996_05 |