反应详情

A mixture of 3,4,4-trifluoro-3-butenoic acid (IV) (19.28 g, 138 mmol), oxalyl chloride (21.8 g, 172 mmol; 15 mL) and two drops of DMF was stirred for 6 hours and distilled at atmospheric pressure under nitrogen. The fraction boiling at 90°-98° C. was collected to give 16.1 g (74%) of the desired product as a dear liquid.

1. distillationdistilled at atmospheric pressure under nitrogen
2. customThe fraction boiling at 90°-98° C. was collected