反应详情

A mixture of 3-(4-benzylphenyl)-6-carboxy-7-hydroxypyrazolo[1,5-a]pyrimidine (1.24 g) and aniline (11 ml) was stirred at 100° C. to 110° C. for 7 hours, and ice-water was put into the reaction mixture. After adding hydrochloric acid to adjust to acid, the reaction mixture was stirred at 0° C. for 1 hour. The precipitate was separated by filtration, washed with methanol-water (1:3)(50 ml), and dried to give the title compound (0.90 g).

1. stirringthe reaction mixture was stirred at 0° C. for 1 hour
2. customThe precipitate was separated by filtration
3. washwashed with methanol-water (1:3)(50 ml)
4. customdried