反应详情

To a mixture of sodium borohydride (2.27 g) and trifluoroacetic acid (50 ml), which was previously prepared under nitrgen atmosphere, was added a solution of 4-methoxycarbonyl-4'-methoxybenzophenone (2.70 g) and methylene chloride (30 ml) at room temperature. After reacting for 24 hours, the reaciton mixture was poured into ice-water, and methylene chloride layer was sepatated. Water layer was further extracted with methylene chloride (50 ml×2).

1. customwas previously prepared under nitrgen atmosphere
2. extractionWater layer was further extracted with methylene chloride (50 ml×2)