Hydrochloric Acid → HCID 178478862, compound

HRID 439886Notes

Reaction equation

HRID 439886 reaction equation
C([NH:8][C@H:9]1[CH2:12][C@H:11]([CH2:13][O:14][N:15]2C(=O)C3C(=CC=CC=3)C2=O)[CH2:10]1)(OC(C)(C)C)=O.[ClH:26]>O>[ClH:26].[ClH:26].[NH2:15][O:14][CH2:13][C@H:11]1[CH2:12][C@H:9]([NH2:8])[CH2:10]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178454092HCID 178454092, compound

Product 1

HCID 178478862HCID 178478862, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Analogously to Example 6, starting from 7.25 g (0.02093 mol) of 2-[trans-3-(N-BOC-amino)-cyclobutylmethoxy]-1H-isoindole-1,3(2H)-dione, 35 ml of water and 30 ml of concentrated hydrochloric acid, the title compound is obtained, m.p. 198° C. (decomp.).

Sources & evidence

ORD record
ord-c716686f1cf345cf968ee0045e8289c7
Source dataset
uspto-grants-1996_05
Patent number
US05516806

Reaction notes

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