HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethylhexyl acrylate → Ethylhexyl 2,4,5-trifluorocinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethylhexyl acrylate | HCID 7636 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Bromo-2,4,5-trifluorobenzene | HCID 67597 | — |
| Reactant | 2,3-Di-tert-butylphenol | HCID 185594 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | Ethylhexyl 2,4,5-trifluorocinnamate | HCID 54005632 | — |
Reaction Steps
3.0 g (14.2 mmol) of 1-bromo-2,4,5-trifluorobenzene are refluxed under protecting gas with 30.0 mmol of 2-ethylhexyl acrylate, 140 mg of palladium on activated charcoal (5% strength), 0.82 g of sodium carbonate and 10 mg of di-tert-butylphenol in 10 ml of dimethylacetamide for 18 hours at 170° C. The catalyst is filtered off, the mixture is diluted with dichloromethane and extracted with water. The crude product is chromatographed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05516932 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-25988816525b43929d9c0169e806735e |
| Source note | uspto-grants-1996_05 |