Sodium → sodium L-ascorbic acid

Participants

Reaction Steps

A first solution is prepared containing high bloom bone gelatin, sodium carboxymethyl cellulose and ascorbic acid (from the sodium salt) in water for injection. A second water for injection solution of chondroitin sulfate is prepared, and the two solutions are combined to yield a solution having a total solids concentration of 2%, and such that on drying the solution yields a gelatin concentration of 79%, sodium carboxymethyl cellulose 10%, ascorbic acid sodium salt 1% and chondroitin sulfate 10%. The combined solutions are then sterilized by passage through a 0.2 μ filter.

Provenance & Evidence