Sodium → sodium L-ascorbic acid

HRID 440210Notes

Reaction equation

HRID 440210 reaction equation
[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([OH:6])=[C:3]1[OH:4].[Na:13]>O>[Na:13].[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([OH:6])=[C:3]1[OH:4]

Participants

4

Reactant 2

HCID 5360545SodiumHCID 54670067L-Ascorbic Acid

Product 1

HCID 66586226sodium L-ascorbic acidYield 1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A first solution is prepared containing high bloom bone gelatin, sodium carboxymethyl cellulose and ascorbic acid (from the sodium salt) in water for injection. A second water for injection solution of chondroitin sulfate is prepared, and the two solutions are combined to yield a solution having a total solids concentration of 2%, and such that on drying the solution yields a gelatin concentration of 79%, sodium carboxymethyl cellulose 10%, ascorbic acid sodium salt 1% and chondroitin sulfate 10%. The combined solutions are then sterilized by passage through a 0.2 μ filter.

Workup

  1. customA first solution is prepared
  2. customto yield a solution
  3. customsuch that on drying the solution

Sources & evidence

ORD record
ord-b750a517c9b34e4988af9f3d8ca39ca5
Source dataset
uspto-grants-1996_05
Patent number
US05518732

Reaction notes

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