Thionyl Chloride → 1-(2-Methoxyphenyl)cyclopropane-1-carbonyl chloride

HRID 440500Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1([C:12]([OH:14])=O)[CH2:11][CH2:10]1.S(Cl)([Cl:17])=O>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1([C:12]([Cl:17])=[O:14])[CH2:11][CH2:10]1

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 184000111-(2-Methoxyphenyl)cyclopropane-1-carboxylic acid

Product 1

HCID 242737911-(2-Methoxyphenyl)cyclopropane-1-carbonyl chloride

Procedure

1-(2-methoxyphenyl)cyclopropane carboxylic acid (19 g) and thionyl chloride (30 ml) were heated under gentle reflux for 2 hours. The solvent was evaporated to yield 1-(2-methoxyphenyl)cyclopropane carbonyl chloride.

Workup

temperatureunder gentle reflux for 2 hours
customThe solvent was evaporated

Sources & evidence

ORD record: ord-9bd963ed53c64b00944548ac86d2f391
Source dataset: uspto-grants-1996_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05519034

Reaction notes

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