Diphosgene → HCID 22404756, compound

HRID 440664Notes

Reaction equation

HRID 440664 reaction equation
[NH2:1][C:2]1[C:10]2[O:9][C:8]([CH3:12])([CH3:11])[CH2:7][C:6]=2[C:5]([O:13][CH3:14])=[CH:4][CH:3]=1.Cl[C:16](OC(Cl)(Cl)Cl)=[O:17]>C1(C)C=CC=CC=1>[CH3:12][C:8]1([CH3:11])[CH2:7][C:6]2[C:5]([O:13][CH3:14])=[CH:4][CH:3]=[C:2]([N:1]=[C:16]=[O:17])[C:10]=2[O:9]1

Participants

4

Reactant 2

HCID 10426DiphosgeneHCID 22404811HCID 22404811, compound

Product 1

HCID 22404756HCID 22404756, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

By the method of Example 1, Step F, 3.70 g (0.0191 mole) of 7-amino-2,3-dihydro-2,2-dimethyl-4-methoxybenzofuran and 3.79 g (0.0191 mole) of trichloromethyl chloroformate were reacted in 100 mL of toluene, yielding 2,3-dihydro-2,2-dimethyl-4-methoxybenzofuran-7-yl isocyanate as a brownish-yellow, viscous oil. The IR spectrum was consistent with the proposed structure.

Sources & evidence

ORD record
ord-b512624987364d388af76e14c41d8b65
Source dataset
uspto-grants-1996_05
Patent number
US05521147

Reaction notes

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