HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphosgene → 4-Bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran-7-yl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphosgene | HCID 10426 | — |
| Reactant | 7-Amino-4-bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran | HCID 22404763 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran-7-yl isocyanate | HCID 22404766 | 104.2% |
Reaction Steps
By the method of Example 1, Step F, 1.6 grams (0.005 mole) of 7-amino-4-bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran and 1.0 gram (0.005 mole) of trichloromethyl chloroformate were reacted in 60 mL of toluene, yielding about 1.7 grams of 4-bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran-7-yl isocyanate. The product was taken to the next step without further characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05521147 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-fe78b072a87f486fb9a83ff9ac23a38b |
| Source note | uspto-grants-1996_05 |