反应详情

By the method of Example 1, Step F, 1.6 grams (0.005 mole) of 7-amino-4-bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran and 1.0 gram (0.005 mole) of trichloromethyl chloroformate were reacted in 60 mL of toluene, yielding about 1.7 grams of 4-bromo-2-ethoxycarbonyl-2,3-dihydro-2-methylbenzofuran-7-yl isocyanate. The product was taken to the next step without further characterization.