Hydrochloric Acid → HCID 178439963, compound

HRID 440844Notes

Reaction equation

[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]3[N:26](C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)[N:25]=[N:24][N:23]=3)=[CH:12][CH:11]=2)[C:7]2[CH:46]=[C:47]([NH:51][C:52]([NH:56][CH3:57])=[N:53][C:54]#[N:55])[CH:48]=[C:49]([Cl:50])[C:6]=2[N:5]=1)[CH2:2][CH3:3].Cl>>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]3[NH:23][N:24]=[N:25][N:26]=3)=[CH:14][CH:15]=2)[C:7]2[CH:46]=[C:47]([NH:51][C:52]([NH:56][CH3:57])=[N:53][C:54]#[N:55])[CH:48]=[C:49]([Cl:50])[C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 178439962HCID 178439962, compound

Product 1

HCID 178439963HCID 178439963, compound

Procedure

Prepared analogously to Example 4d from 4'-[(2-n-propyl-4-chloro-6-(2-cyano-3-methyl-guanidino)-1H-benzimidazol-1-yl]-methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)biphenyl and methanolic hydrochloric acid.

Sources & evidence

ORD record: ord-6ed7859a2103451384375a0a1ee599c0
Source dataset: uspto-grants-1996_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05521177

Reaction notes

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