Diisopropylamine → HCID 178439926, compound

HRID 440849Notes

Reaction equation

HRID 440849 reaction equation
[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]3[NH:26][N:25]=[N:24][N:23]=3)=[CH:12][CH:11]=2)[C:7]2[CH:27]=[C:28]([NH:32][C:33](=[N:42][C:43]#[N:44])OOC3C=CC=CC=3)[CH:29]=[C:30]([CH3:31])[C:6]=2[N:5]=1)[CH2:2][CH3:3].[CH:45]([NH:48][CH:49]([CH3:51])[CH3:50])([CH3:47])[CH3:46]>C(O)(C)C>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]3[NH:23][N:24]=[N:25][N:26]=3)=[CH:14][CH:15]=2)[C:7]2[CH:27]=[C:28]([NH:32][C:33]([N:48]([CH:49]([CH3:51])[CH3:50])[CH:45]([CH3:47])[CH3:46])=[N:42][C:43]#[N:44])[CH:29]=[C:30]([CH3:31])[C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 7912DiisopropylamineHCID 178439930HCID 178439930, compound

Product 1

HCID 178439926HCID 178439926, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Prepared analogously to Example 1c from 4'-[[2-n-propyl-4-methyl-6-(2-phenoxy-3-cyano-isoureido)-1H-benzimidazol -1-yl]-methyl]-2-(1H-tetrazol-5-yl)-biphenyl and diisopropylamine in boiling isopropanol.

Sources & evidence

ORD record
ord-5bda0f9937884de2978d13c8b26e8619
Source dataset
uspto-grants-1996_05
Patent number
US05521177

Reaction notes

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