Dimethylamine → HCID 178437455, compound

HRID 440855Notes

Reaction equation

HRID 440855 reaction equation
[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:21]3[NH:25][N:24]=[N:23][N:22]=3)=[CH:11][CH:10]=2)[C:6]2[CH:26]=[C:27]([NH:31][C:32](=[N:41][C:42]#[N:43])OOC3C=CC=CC=3)[CH:28]=[C:29]([CH3:30])[C:5]=2[N:4]=1)[CH3:2].[CH3:44][NH:45][CH3:46]>C(O)(C)C>[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:21]3[NH:22][N:23]=[N:24][N:25]=3)=[CH:13][CH:14]=2)[C:6]2[CH:26]=[C:27]([NH:31][C:32]([N:45]([CH3:46])[CH3:44])=[N:41][C:42]#[N:43])[CH:28]=[C:29]([CH3:30])[C:5]=2[N:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 674DimethylamineHCID 178437458HCID 178437458, compound

Product 1

HCID 178437455HCID 178437455, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Prepared analogously to Example 6d from 4'-[[2-ethyl-4-methyl-6-(2-phenoxy-3-cyano-isoureido)-1H-benzimidazol-1-yl]-methyl]-2-(1H-tetrazol-5-yl)-biphenyl and dimethylamine in isopropanol.

Sources & evidence

ORD record
ord-26c997ffdcdf443f8213d33a09d301ee
Source dataset
uspto-grants-1996_05
Patent number
US05521177

Reaction notes

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