Hydrochloric Acid → N-[5-(n-butylaminoacetylamino)-4-nitro-2-phenoxyphenyl]methanesulfonamide hydrochloride

HRID 441128Notes

Reaction equation

HRID 441128 reaction equation
[CH2:1]([NH:5][CH2:6][C:7]([NH:9][C:10]1[C:11]([N+:28]([O-:30])=[O:29])=[CH:12][C:13]([O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:14]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[CH:15]=1)=[O:8])[CH2:2][CH2:3][CH3:4].[ClH:31]>CC(C)=O>[ClH:31].[CH2:1]([NH:5][CH2:6][C:7]([NH:9][C:10]1[C:11]([N+:28]([O-:30])=[O:29])=[CH:12][C:13]([O:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[C:14]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[CH:15]=1)=[O:8])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15285982N-[5-(n-butylaminoacetylamino)4-nitro-2-phenoxyphenyl]methanesulfonamide

Product 1

HCID 67732821N-[5-(n-butylaminoacetylamino)-4-nitro-2-phenoxyphenyl]methanesulfonamide hydrochloride

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To 15 ml of an acetone solution containing 0.30 g of N-[5-(n-butylaminoacetylamino)-4-nitro-2-phenoxyphenyl]methanesulfonamide obtained by the procedure of Example 1 was added 0.06 ml of 12N hydrochloric acid, followed by stirring for 15 minutes. The precipitate was collected by filtration and washed with acetone to give 0.24 g of N-[5-(n-butylaminoacetylamino)-4-nitro-2-phenoxyphenyl]methanesulfonamide hydrochloride as yellow crystals.

Workup

  1. customobtained by the procedure of Example 1
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with acetone

Sources & evidence

ORD record
ord-799ecc7ef5e949be88a7921a0e6b5b2d
Source dataset
uspto-grants-1996_05
Patent number
US05521311

Reaction notes

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