Methyl iodide → HCID 69948022, compound

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A mixture of 5-{4-[2-(4-methylphenyl)benzoylamino]benzoyl}-1-(4-methyl-1-piperazinylcarbonyl)methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2(2H)-one (110 mg) and methyl iodide (76.1 mg) in dichloromethane (10 ml) was stirred at ambient temperature overnight and a precipitate was filtered to give 4-{5-{4-[2-(4-methylphenyl)benzoylamino]benzoyl}-2-oxo-1,3,4 ,5-tetrahydro-2H-1,5-benzodiazepin-1-yl) acetyl-1,1-dimethylpiperazinium iodide (118 mg).

Provenance & Evidence