反应详情

Following a procedure similar to that described in Example 1 but using 3.4 g. sodium in 300 ml. dry acetone, 22.5 g. hexanamidine hydrochloride, and 25.9 g. 4-chlorophenyl isothiocyanate in 150 ml. dry acetone there was obtained 1-(4-chlorophenyl)-3-(hexanimidoyl)-2-thiourea, m.p. 100°-102° C. (from benzene-n-pentane); hydrochloride (21 g.), m.p. 175° C. (from acetonitrile).