HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 178444021, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 4-Fluorophenyl isothiocyanate | HCID 15241 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Heptanimidamide hydrochloride | HCID 14144282 | — |
| Solvent | Benzene n-pentane | HCID 19707280 | — |
| Product | HCID 178444021 | HCID 178444021 | — |
Reaction Steps
Following a procedure similar to that described in Example 1 but using 1.6 g. sodium in 200 ml. dry acetone, 12.3 g. heptanamidine hydrochloride, and 11.6 g. 4-fluorophenyl isothiocyanate (b.p. 48° C./0.025 mm.; prepared from 4-fluoroaniline) in 50 ml. dry acetone there was obtained 1-(4-fluorophenyl)-3-(heptanimidoyl)-2-thiourea, m.p. 75°-76° C. (from benzene-n-pentane); hydrochloride (17.1 g.), m.p. 155° C. (from acetonitrile).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04039575 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-6e9b11edbfdb4f979c7d36588f5c941a |
| Source note | uspto-grants-1977_08 |