Ammonia → HCID 135623125, compound

HRID 441341Notes

Reaction equation

HRID 441341 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=O)[CH2:9][S:10]([CH3:12])=[O:11].[NH3:14]>>[NH:14]=[C:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[OH:1])[CH2:9][S:10]([CH3:12])=[O:11]

Participants

3

Reactant 2

HCID 222Ammonia2×HCID 578088HCID 578088, compound

Product 1

HCID 135623125HCID 135623125, compoundYield 79%

Procedure

A solution of 2'-hydroxy-2-(methylsulfinyl)acetophenone (23.5 g, 0.12 mole) in liquid ammonia (450 ml) was stirred at -33° for 9 hrs. The ammonia was allowed to evaporate. The residue was recrystallized from methanol to give yellow crystals (18.5 g, 79%), mp 194°-195°.

Workup

  1. customto evaporate
  2. customThe residue was recrystallized from methanol

Sources & evidence

ORD record
ord-ceb18f29f8764ff5ac5be5c783fceb03
Source dataset
uspto-grants-1977_08
Patent number
US04039579

Reaction notes

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