Butylamine → HCID 135623127, compound

HRID 441343Notes

Reaction equation

HRID 441343 reaction equation
[OH:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:10](=O)[CH2:11][S:12]([CH3:14])=[O:13].[CH2:16]([NH2:20])[CH2:17][CH2:18][CH3:19]>>[CH2:16]([N:20]=[C:10]([C:3]1[CH:4]=[CH:5][CH:6]=[C:7]([O:8][CH3:9])[C:2]=1[OH:1])[CH2:11][S:12]([CH3:14])=[O:13])[CH2:17][CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 8007ButylamineHCID 124350051-(2-Hydroxy-3-methoxyphenyl)-2-(methanesulfinyl)ethan-1-one

Product 1

HCID 135623127HCID 135623127, compoundYield 97%

Procedure

A solution of 2'-hydroxy-3'-methoxy-2-(methylsulfinyl)acetophenone (5 g, 0.022 mole) in n-butylamine (25 ml) was stirred at room temperature for 24 hrs. The reaction mixture was poured into petroleum ether (200 ml) and the product, which precipitated, was filtered off. Recrystallization from ethylacetate gave yellow crystals (6.0 g, 97%), mp 125°-127°.

Workup

  1. customthe product, which precipitated
  2. filtrationwas filtered off
  3. customRecrystallization from ethylacetate

Sources & evidence

ORD record
ord-cf8129365b33409db43e561439b4dbb8
Source dataset
uspto-grants-1977_08
Patent number
US04039579

Reaction notes

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