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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 441418Generated: October 30, 2026

Acetic Acid → 2-(4-Phenoxymethylphenoxy)-propionic acid

https://huagongshe.com/reaction/441418

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
Reactant2-(4-Phenoxymethylphenoxy)-propionamideHCID 21421172—
SolventWaterHCID 962—
Product2-(4-Phenoxymethylphenoxy)-propionic acidHCID 21421173—

Reaction Steps

A mixture of 1 g. of 2-(4-phenoxymethylphenoxy)-propionamide, 2 ml. of concentrated hydrochlorid acid, and 2 ml. of acetic acid is refluxed for 48 hours and, after adding water, worked up as usual, yielding 2-(4-phenoxymethylphenoxy)-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04039683
Source datasetuspto-grants-1977_08
ORD IDord-0f51d2afa2554271ac590ad40ead67ab
Source noteuspto-grants-1977_08