Ethylamine → HCID 6015846, compound

HRID 441562Notes

Reaction equation

HRID 441562 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)/[CH:5]=[CH:6]/[C:7](Cl)=[O:8].[CH2:13]([NH2:15])[CH3:14]>C1C=CC=CC=1.CCOCC>[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)/[CH:5]=[CH:6]/[C:7]([NH:15][CH2:13][CH3:14])=[O:8]

Participants

5

Reactant 2

HCID 6341EthylamineHCID 11008963(2E)-3-(3-chlorophenyl)prop-2-enoyl chloride

Product 1

HCID 6015846HCID 6015846, compound

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 3283Diethyl EtherSolvent

Procedure

Trans 3-chlorocinnamoyl chloride (4.4 g) in dry benzene (75 ml) was allowed to react with an excess of ethylamine in dry ether (75 ml) according to the procedure of Example 2. Trans 3-chloro-N-ethylcinnamamide, m.p. 87°-88° C., was obtained which had NMR, IR, and elemental analysis consistent with this structure.

Sources & evidence

ORD record
ord-6d07ba44392049e0bcb0fec8c65e091e
Source dataset
uspto-grants-1977_08
Patent number
US04041071

Reaction notes

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