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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 441743Generated: October 31, 2026

Methanol → 2-Amino-5-bromo-3-methoxypyrazine

https://huagongshe.com/reaction/441743

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant2-Amino-3,5-dibromopyrazineHCID 620004—
ReactantSodiumHCID 5360545—
Product2-Amino-5-bromo-3-methoxypyrazineHCID 11344724—

Reaction Steps

2-Amino-3,5-dibromopyrazine (7 g.) is boiled for about 9 hours with 0.65 g. sodium in 18.5 ml. methanol to give 2-amino-3-methoxy-5-bromopyrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04042586
Source datasetuspto-grants-1977_08
ORD IDord-f304e8276e06497bab8cbd05771bd48c
Source noteuspto-grants-1977_08