反应详情

This intermediate was obtained according to general procedure I from 8-fluoro-3,4,4a,8a-tetrahydro-1H-quinolin-2-one (515 mg, 3.12 mmol) and NBS (583 mg, 3.27 mmol) after flash chromatography on silica gel (hexanes/ethyl acetate, 5/1, Rf=0.32) as white solid (647 mg, 2.65 mmol, 85%).

1. customThis intermediate was obtained