HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 2-Benzyl-6-methoxyisoquinolinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 6-Methoxyisoquinoline | HCID 11040978 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Benzyl-6-methoxyisoquinolinium bromide | HCID 21418213 | — |
Reaction Steps
6-Methoxyisoquinoline (1.6 g) and benzyl bromide (2 ml) in acetone (75 ml) were heated under reflux for 1 hour. The mixture was diluted with ether and cooled to 0°. The solid was filtered off and recrystallised from methanol/ether, and had m.p. 155°-158°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04042697 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-a515023c47354e99bfa7c2376c17c423 |
| Source note | uspto-grants-1977_08 |