反应详情

6-Methoxyisoquinoline (1.6 g) and benzyl bromide (2 ml) in acetone (75 ml) were heated under reflux for 1 hour. The mixture was diluted with ether and cooled to 0°. The solid was filtered off and recrystallised from methanol/ether, and had m.p. 155°-158°.

1. temperatureunder reflux for 1 hour
2. temperaturecooled to 0°
3. filtrationThe solid was filtered off
4. customrecrystallised from methanol/ether