HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 5,5-Dimethyl-10-[4-(pyrrolidino)butyryloxy]-2-phenethyl-8-(2-tetradecyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 4-(Pyrrolidin-1-yl)butanoic acid hydrochloride | HCID 14855682 | — |
| Reactant | 5,5-Dimethyl-10-hydroxy-2-phenethyl-8-(2-tetradecyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine | HCID 21418116 | — |
| Product | 5,5-Dimethyl-10-[4-(pyrrolidino)butyryloxy]-2-phenethyl-8-(2-tetradecyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride | HCID 21418149 | — |
Reaction Steps
5,5-Dimethyl-10-hydroxy-2-phenethyl-8-(2-tetradecyl)-1,2,3,4-tetrahydro-5H-[ 1]benzopyrano[3,4-d]pyridine, γ-pyrrolidinobutyric acid hydrochloride and dicyclohexylcarbodiimide are reacted in equimolar amounts according to Example 1 to produce the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04042694 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-dd22514682b94b439e09aa456bd562b5 |
| Source note | uspto-grants-1977_08 |